RUNX1 anticorps (N-Term)
Aperçu rapide pour RUNX1 anticorps (N-Term) (ABIN2780380)
Antigène
Voir toutes RUNX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Séquence
- KMPAAPRGPA QGEAAARTRS RDASTSRRFT PPSTALSPGK MSEALPLGAP
-
Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
-
Attributs du produit
- This is a rabbit polyclonal antibody against RUNX1. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Affinity Purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human RUNX1
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 107 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
-
Autre désignation
- RUNX1
-
Sujet
-
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia.
Alias Symbols: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1
Protein Interaction Partner: YAP1, UBC, HDAC11, SOX2, SMAD3, CTBP1, RUNX1, FOXP3, NCOR2, MYC, NOTCH1, UXT, CTBP2, KAT6A, PML, CREBBP, CBFB, PRMT1, HLA-DMA, HDAC2, HDAC1, CBFA2T3, RUNX1T1, CBFA2T2, ELAVL1, DNMT1, SPEN, RBM14, KMT2A, COPRS, HDAC3, TAL1, CDK1, SMARCC1, SMARCB1, SMARCA4,
Protein Size: 107 -
Poids moléculaire
- 12 kDa
-
ID gène
- 861
-
NCBI Accession
- NM_001001890
-
UniProt
- Q01196
Antigène
-